Cover Feature: Ultrafast Single-Scan 2D NMR Spectroscopic Detection of a PHIP-Hyperpolarized Protease Inhibitor (Chem. Eur. J. 16/2019)

Cover Feature: Ultrafast Single-Scan 2D NMR Spectroscopic Detection of a PHIP-Hyperpolarized Protease Inhibitor (Chem. Eur. J. 16/2019) Иное

Журнал

Chemistry - A European Journal
ISSN: 0947-6539

Вых. Данные

Год: 2019, Том: 25, Номер: 16, Страницы: 3966-3966 Страниц : 1 DOI: 10.1002/chem.201900875

Авторы

Kiryutin Alexey S. ^1,2 , Sauer Grit ³ , Tietze Daniel ³ , Brodrecht Martin ³ , Knecht Stephan ³ , Yurkovskaya Alexandra V. ^1,2 , Ivanov Konstantin L. ^1,2 , Avrutina Olga ⁴ , Kolmar Harald ⁴ , Buntkowsky Gerd ³

Организации

1	International Tomography Center Institutskaya 3A, Novosibirsk (Russia)
2	Novosibirsk State University Pirogova 2, Novosibirsk, 630090 (Russia)
3	Eduard-Zintl-Institut faer Anorganische und Physikalische Chemie Technische Universitфaet Darmstadt Alarich-Weiss-Straße 8, 64287 Darmstadt (Germany)
4	Clemens-Schoepf-Institut faer Organische Chemie und Biochemie Technische Universitaet Darmstadt

Two-dimensional NMR spectroscopy is one of the most important spectroscopic tools for the investigation of biological macromolecules. Because of the low sensitivity of NMR it usually takes from several minutes to many hours to record such a spectrum. In this work, it is shown that a bioactive derivative of the sunflower trypsin inhibitor-1 (SFTI-1), a tetradecapeptide, can be detected by the combination of parahydrogen-induced polarization (PHIP) and ultrafast 2D-NMR spectroscopy in less than ten seconds. More information can be found in the Communication by G. Buntkowsky et al. on page 4025.

Kiryutin A.S. , Sauer G. , Tietze D. , Brodrecht M. , Knecht S. , Yurkovskaya A.V. , Ivanov K.L. , Avrutina O. , Kolmar H. , Buntkowsky G.
Cover Feature: Ultrafast Single-Scan 2D NMR Spectroscopic Detection of a PHIP-Hyperpolarized Protease Inhibitor (Chem. Eur. J. 16/2019)
Chemistry - A European Journal. 2019. V.25. N16. P.3966-3966. DOI: 10.1002/chem.201900875 OpenAlex

Поступила в редакцию:	4 янв. 2019 г.
Принята к публикации:	30 янв. 2019 г.
Опубликована online:	30 янв. 2019 г.
Опубликована в печати:	17 февр. 2019 г.

OpenAlex:

W2923686352

БД	Цитирований
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