Polarization of low-g nuclei by transferring spin order of parahydrogen at high magnetic fields

Polarization of low-g nuclei by transferring spin order of parahydrogen at high magnetic fields Full article

Journal

Journal of Magnetic Resonance
ISSN: 1090-7807

Output data

Year: 2019, Volume: 309, Article number : 106594, Pages count : 7 DOI: 10.1016/j.jmr.2019.106594

Authors

Kozinenko Vitaly P. ^1,2 , Kiryutin Alexey S. ^1,2 , Yurkovskaya Alexandra V. ^1,2 , Ivanov Konstantin L. ^1,2

Affiliations

1	International Tomography Center, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia
2	Novosibirsk State University, Novosibirsk 630090, Russia

In this work, we optimize the performance of a previously proposed method for transferring parahydrogen induced polarization to “insensitive” spin-1/2 NMR (Nuclear Magnetic Resonance) nuclei, which have low gyromagnetic ratio and low natural abundance. By optimizing the reaction conditions and pressure of the parahydrogen gas and using adiabatically switched radiofrequency fields we achieve high polarization transfer efficiency and report carbon spin polarization of dimethyl acetylene dicarboxylate reaching 35%, which corresponds to 13C NMR signal enhancements of about 43,000 at 9.4 Tesla. Such polarization levels allow one to work with mM concentrations at natural carbon abundance and to detect 13C NMR signal in single scan. In combination with a pseudo phase cycle, the polarization transfer method used here also enables efficient suppression of unwanted background signals.

Kozinenko V.P. , Kiryutin A.S. , Yurkovskaya A.V. , Ivanov K.L.
Polarization of low-g nuclei by transferring spin order of parahydrogen at high magnetic fields
Journal of Magnetic Resonance. 2019. V.309. 106594 :1-7. DOI: 10.1016/j.jmr.2019.106594

Submitted:	May 18, 2019
Accepted:	Sep 7, 2019
Published online:	Sep 19, 2019

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