2-Imidazoline Nitroxide Derivatives of Cymantrene

2-Imidazoline Nitroxide Derivatives of Cymantrene Full article

Journal

Molecules
ISSN: 1420-3049

Output data

Year: 2022, Volume: 27, Number: 21, Article number : 7545, Pages count : 11 DOI: 10.3390/molecules27217545

Authors

Maryunina Kseniya ¹ , Letyagin Gleb ^1,2 , Romanenko Galina ¹ , Bogomyakov Artem ^1,2,3 , Morozov Vitaly ¹ , Tumanov Sergey ^1,2 , Veber Sergey ^1,2 , Fedin Matvey ^1,2 , Saverina Evgeniya ³ , Syroeshkin Mikhail ³ , Egorov Mikhail ³ , Ovcharenko Victor ^1,3

Affiliations

1	International Tomography Center SB RAS, Institutskaya Str. 3a, 630090 Novosibirsk, Russia
2	Novosibirsk State University, Pirogova Str. 1, 630090 Novosibirsk, Russia
3	N. D. Zelinsky Institute of Organic Chemistry RAS, Leninsky Prospect, 47, 119991 Moscow, Russia

The 2-imidazoline nitroxide derivatives of cymantrene—2-(η5-cyclopentadienyl)tricarbonylmanganese(I)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole-3-oxide-1-oxyl (NNMn) and 2-(η5-cyclopentadienyl)tricarbonylmanganese(I)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole-1-oxyl (INMn) were synthesized. It was shown that NNMn and INMn exhibit a sufficiently high kinetic stability both in solids and in solutions under normal conditions. Their structural characteristics, magnetic properties and electrochemical behavior are close to Re(I) analogs. This opens the prospect of using paramagnetic cymantrenes as prototypes in the design of Re(I) half-sandwiched derivatives for theranostics, where therapy is combined with diagnostics by magnetic resonance imaging due to the contrast properties of nitroxide radicals.

Maryunina K. , Letyagin G. , Romanenko G. , Bogomyakov A. , Morozov V. , Tumanov S. , Veber S. , Fedin M. , Saverina E. , Syroeshkin M. , Egorov M. , Ovcharenko V.
2-Imidazoline Nitroxide Derivatives of Cymantrene
Molecules. 2022. V.27. N21. 7545 :1-11. DOI: 10.3390/molecules27217545 WOS Scopus OpenAlex

Submitted:	Oct 10, 2022
Published print:	Nov 3, 2022

Web of science:	WOS:000883628700001
Scopus:	2-s2.0-85141632629
OpenAlex:	W4308331691

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Scopus	2
Web of science	2