Photooxidation of Histidine by 3,3',4,4'-Benzophenone Tetracarboxylic Acid in Aqueous Solution: Time-Resolved and Field-Dependent CIDNP Study

Photooxidation of Histidine by 3,3',4,4'-Benzophenone Tetracarboxylic Acid in Aqueous Solution: Time-Resolved and Field-Dependent CIDNP Study Научная публикация

Журнал

Applied Magnetic Resonance
ISSN: 0937-9347

Вых. Данные

Год: 2014, Том: 45, Номер: 10, Страницы: 1019-1033 Страниц : 15 DOI: 10.1007/s00723-014-0577-8

Ключевые слова

coupled electron-transfer, density-functional calculations, dynamic nuclear-polarization, epr continuous-flow, amino-acids, radical pairs, peptides, tyrosine, model, oxidation

Авторы

Panov Mikhail S. ^1,2 , Saprygina Natalya N. ^1,2 , Morozova Olga B. ¹ , Kiryutin Alexey S. ¹ , Grishin Yuri A. ³ , Yurkovskaya Alexandra V. ^1,2

Организации

1	International Tomography Center SB RAS, Institutskaya 3a, 630090 Novosibirsk, Russia
2	Novosibirsk State University, Pirogova 2, 630090 Novosibirsk, Russia
3	Institute of Chemical Kinetics and Combustion SB RAS, Institutskaya 3, 630090 Novosibirsk, Russia

The photooxidation reaction between 3,3',4,4'-benzophenone tetracarboxylic acid (TCBP) and l-histidine (His) has been investigated in neutral aqueous solution using the technique of chemically induced dynamic nuclear polarization (CIDNP). Relative values of C-13 isotropic hyperfine couplings in the TCBP and His radicals were obtained from the C-13-time-resolved CIDNP spectrum, recorded during the photoreaction of TCBP with His at natural abundance of the magnetic isotope C-13. Good agreement was found for the hyperfine coupling constants of the TCBP ketyl radical calculated using methods of density functional theory, and those obtained from the C-13-time-resolved CIDNP spectrum. The mechanism of the quenching reaction of triplet-excited TCBP by His in neutral aqueous solution was established. H-1 CIDNP field dependencies for the photoreaction of TCBP with His were obtained and the g-factor of the histidyl radical was found.

Panov M.S. , Saprygina N.N. , Morozova O.B. , Kiryutin A.S. , Grishin Y.A. , Yurkovskaya A.V.
Photooxidation of Histidine by 3,3',4,4'-Benzophenone Tetracarboxylic Acid in Aqueous Solution: Time-Resolved and Field-Dependent CIDNP Study
Applied Magnetic Resonance. 2014. V.45. N10. P.1019-1033. DOI: 10.1007/s00723-014-0577-8 WOS OpenAlex

Поступила в редакцию:	26 июн. 2014 г.
Опубликована online:	9 сент. 2014 г.

Web of science:	WOS:000344058800006
OpenAlex:	W2062325268

БД	Цитирований
OpenAlex	19