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Photooxidation of Histidine by 3,3',4,4'-Benzophenone Tetracarboxylic Acid in Aqueous Solution: Time-Resolved and Field-Dependent CIDNP Study Full article

Journal Applied Magnetic Resonance
ISSN: 0937-9347
Output data Year: 2014, Volume: 45, Number: 10, Pages: 1019-1033 Pages count : 15 DOI: 10.1007/s00723-014-0577-8
Tags coupled electron-transfer, density-functional calculations, dynamic nuclear-polarization, epr continuous-flow, amino-acids, radical pairs, peptides, tyrosine, model, oxidation
Authors Panov Mikhail S. 1,2 , Saprygina Natalya N. 1,2 , Morozova Olga B. 1 , Kiryutin Alexey S. 1 , Grishin Yuri A. 3 , Yurkovskaya Alexandra V. 1,2
Affiliations
1 International Tomography Center SB RAS, Institutskaya 3a, 630090 Novosibirsk, Russia
2 Novosibirsk State University, Pirogova 2, 630090 Novosibirsk, Russia
3 Institute of Chemical Kinetics and Combustion SB RAS, Institutskaya 3, 630090 Novosibirsk, Russia

Abstract: The photooxidation reaction between 3,3',4,4'-benzophenone tetracarboxylic acid (TCBP) and l-histidine (His) has been investigated in neutral aqueous solution using the technique of chemically induced dynamic nuclear polarization (CIDNP). Relative values of C-13 isotropic hyperfine couplings in the TCBP and His radicals were obtained from the C-13-time-resolved CIDNP spectrum, recorded during the photoreaction of TCBP with His at natural abundance of the magnetic isotope C-13. Good agreement was found for the hyperfine coupling constants of the TCBP ketyl radical calculated using methods of density functional theory, and those obtained from the C-13-time-resolved CIDNP spectrum. The mechanism of the quenching reaction of triplet-excited TCBP by His in neutral aqueous solution was established. H-1 CIDNP field dependencies for the photoreaction of TCBP with His were obtained and the g-factor of the histidyl radical was found.
Cite: Panov M.S. , Saprygina N.N. , Morozova O.B. , Kiryutin A.S. , Grishin Y.A. , Yurkovskaya A.V.
Photooxidation of Histidine by 3,3',4,4'-Benzophenone Tetracarboxylic Acid in Aqueous Solution: Time-Resolved and Field-Dependent CIDNP Study
Applied Magnetic Resonance. 2014. V.45. N10. P.1019-1033. DOI: 10.1007/s00723-014-0577-8 WOS OpenAlex
Dates:
Submitted: Jun 26, 2014
Published online: Sep 9, 2014
Identifiers:
Web of science: WOS:000344058800006
OpenAlex: W2062325268
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