Photophysical properties of 2,3-bis(2-pyridyl)pyrazine (dpp) – A prospective bridging ligand for polymetallic light-activated anticancer complexes

Photophysical properties of 2,3-bis(2-pyridyl)pyrazine (dpp) – A prospective bridging ligand for polymetallic light-activated anticancer complexes Научная публикация

Журнал

Journal of Photochemistry and Photobiology A: Chemistry
ISSN: 1010-6030

Вых. Данные

Год: 2026, Том: 482, Номер статьи : 117541, Страниц : DOI: 10.1016/j.jphotochem.2026.117541

Авторы

Meshcheryakova Valeriya A. ^1,2 , Tsentalovich Yuri P. ³ , Ershov Kirill S. ² , Baklanov Alexei V. ² , Glebov Evgeni M. ^1,2

Организации

1	Novosibirsk State University, 2 Pirogova Str., 630090 Novosibirsk, Russian Federation
2	Voevodsky Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Sciences, 3 Institutskaya Str., 630090 Novosibirsk, Russian Federation
3	International Tomography Center, Siberian Branch of the Russian Academy of Sciences, 3a Institutskaya Str., 630090 Novosibirsk, Russian Federation

Photophysics of 2,3-bis(2-pyridyl)pyrazine (dpp) considered as a promising bridging ligand for the creation of polymetallic platinum metal complexes exhibiting light-activated cytotoxicity, was studied by means of stationary and time-resolved methods. Dpp is rather photostable in aqueous and acetonitrile solutions and non-luminescent. The triplet state of dpp (3dpp*) was detected upon n → π* excitation (355 nm) both in aqueous and acetonitrile solutions. In addition, dpp excitation at 266 nm (π → π* transition) in aqueous solutions resulted in formation of another excited state of triplet nature, which was not observed in CH3CN solutions. This state was interpreted as the triplet state of the protonated form 3dppH+*. Spectral and kinetic parameters of both triplet states are determined or estimated. Quantum yield of singlet oxygen formation in acetonitrile upon 355 nm excitation was measured to be (12 ± 1)%. The obtained information can be useful for describing the photophysics of metal complexes containing dpp, especially in the case of excitation into the intraligand (IL) absorption bands.

Meshcheryakova V.A. , Tsentalovich Y.P. , Ershov K.S. , Baklanov A.V. , Glebov E.M.
Photophysical properties of 2,3-bis(2-pyridyl)pyrazine (dpp) – A prospective bridging ligand for polymetallic light-activated anticancer complexes
Journal of Photochemistry and Photobiology A: Chemistry. 2026. V.482. 117541 . DOI: 10.1016/j.jphotochem.2026.117541 WOS Scopus OpenAlex

Поступила в редакцию:	7 мая 2026 г.
Принята к публикации:	22 июл. 2026 г.
Опубликована online:	25 июл. 2026 г.
Опубликована в печати:	1 янв. 2027 г.

≡ Web of science:	WOS:001838047600001
≡ Scopus:	2-s2.0-105045845509
≡ OpenAlex:	W7171328164